April 28, 2023 by admin aurigene Efficacy and safety of highly selective novel IRAK4 inhibitors for treatment of ABC-DLBCL
April 28, 2023 by admin aurigene Potent and selective inhibition of CDK7 by novel covalent inhibitors
April 28, 2023 by admin aurigene Identification of novel covalent inhibitors of K-Ras G12C that are efficacious in a xenograft model of NSCLC
April 28, 2023 by admin aurigene Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells
April 28, 2023 by admin aurigene Novel inhibitors of protein arginine methyltransferase 5 (PRMT5) for the treatment of solid tumors
April 28, 2023 by admin aurigene Identification of a novel highly selective and orally bioavailable preclinical candidate for CDK7 covalent inhibition
April 28, 2023 by admin aurigene Functional antagonism of VSIG8-mediated immune suppression by oral VISTA agents
April 28, 2023 by admin aurigene Targeting CD47- SIRPα interaction by novel peptide-based antagonists
April 28, 2023 by admin aurigene Immune-mediated anti-tumor activity with a clinical stage BET bromodomain inhibitor ODM-207 in pre-clinical models
April 28, 2023 by admin aurigene Potent small molecule compounds that selectively inhibit proliferation of ABC-DLBCL cell lines
