April 28, 2023 by admin aurigene Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders
April 28, 2023 by admin aurigene Small Molecule Agents Targeting PD-1 Checkpoint Pathway for Cancer Immunotherapy: Mechanisms of Action and Other Considerations for Their Advanced Development
April 28, 2023 by admin aurigene Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action
April 28, 2023 by admin aurigene Discovery of orally bioavailable SMARCA2/4 dual degraders for treatment of acute myeloid leukemia
April 28, 2023 by admin aurigene Evaluation of AU-18069, a novel small molecule CBP/p300 bromodomain inhibitor for the treatment of cancers
April 28, 2023 by admin aurigene AUR103 an oral small molecule CD47 antagonist in combination with azacytidine and bortezomib exhibits potent anti-tumor activity in myeloma and leukemia models in vitro
April 28, 2023 by admin aurigene PROTACs: Current Trends in Protein Degradation by Proteolysis-Targeting Chimeras
April 28, 2023 by admin aurigene Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations