Efficient throughput method for hygroscopicity classification of active and inactive pharmaceutical ingredients by water vapor sorption analysis

Novel inhibitors of nicotinamide phosphoribosyltransferase (NAMPT)

Identification of potent BET bromodomain inhibitors for treatment of cancer

Equipotent antagonism, transient immune activation and excellent antitumor efficacy with a peptide inhibitor of PD-1 immune checkpoint pathway

Discovery of potent & selective retinoid related orphan receptor gamma (ROR-gamma) inverse agonists for the treatment of TH17 mediated diseases

Equipotent antagonism towards both ligands and excellent anti-tumor efficacy with a peptide inhibitor of PD-1 immune checkpoint pathway

Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia

Novel inhibitors of nicotinamide phosphoribosyltransferase and their evaluation in combination with bortezomib

X-ray structure of PTP1B in complex with a new PTP1B inhibitor

Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion